One hundred years ago, the Ottoman regime, best known as that of the Young Turks, began a series of actions that led to the genocides of Armenians, Assyrians, and Greeks that only ended in 1923. The articles presented in this special issue of Genocide Studies International deal with the competing interpretations of why the Armenian Genocide occurred, with what the German archives reveal about it and any German responsibility for it, and with Turkish denial since the 1960s. They also make major contributions to understanding the lesser-known Ottoman genocides, those against the Assyrians and the Greeks. There are also questions raised about the concept of genocide and its relation to ethnic cleansing, massacres, deportation, and war. Overall, there is the theme of the complexity of genocide: modes, techniques, and motives. Careful consideration of the Ottoman genocides deepens our understanding of what genocide is and how it can be enacted. What must be averted is letting its complexity become a cover for denial.