Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis

CA Emdin, K Rahimi, B Neal, T Callender, V Perkovic… - Jama, 2015 - jamanetwork.com
Importance Lowering blood pressure (BP) is widely used to reduce vascular risk in
individuals with diabetes. Objective To determine the associations between BP–lowering
treatment and vascular disease in type 2 diabetes. Data Sources and Study Selection We
searched MEDLINE for large-scale randomized controlled trials of BP–lowering treatment
including patients with diabetes, published between January 1966 and October 2014. Data
Extraction and Synthesis Two reviewers independently extracted study characteristics and …