Police maltreatment, whether experienced personally or indirectly through one’s family or friends, represents a potentially harmful stressor, particularly for minority populations. We address this issue by investigating: (1) how waist circumference (WC) varies by personal and vicarious exposure to unfair treatment by police (UTBP); and (2) to what extent exposure to UTBP explains the black-white disparity in WC. We employed data collected from a community-based sample of black (n = 601) and white (n = 608) adults living in Nashville-Davidson county Tennessee to address these questions. Results from our final linear regression model showed that those who reported vicarious UTBP had WCs that were approximately 2 in. greater than those who did not (b = 2.03; p = 0.003). While personal UTBP was not linked to higher WC, a post-hoc analysis suggested that our ability to detect an association was complicated by selection. Binary mediation analysis revealed that differential exposure to vicarious UTBP accounted for approximately 12% of the black-white WC disparity among women. We found no black-white differences in WC among men. The association between vicarious UTBP and WC did not vary by age, race, or gender. Overall, our findings point toward the role of discriminatory policing as a potential upstream contributor to racial disparities in health.