Since Bruno Latour's discussion of a Sakhalin island map used by La Pérouse as part of a global network of “immutable mobiles,” the commensurability of European and non-European knowledge has become an important issue for historians of science. But recent studies have challenged these dichotomous categories as reductive and inadequate for understanding the fluid nature of identities, their relational origins, and their historically constituted character. Itineraries of knowledge transfer, traced in the wake of objects and individuals, offer a powerful heuristic alternative, bypassing artificial epistemological divides and avoiding the limited scale of national or monolingual frames. Approaches that place undue emphasis either on the omnipotence of the imperial center or the centrality of the colonial periphery see only half the picture. Instead, practices of knowledge collection, codification, elaboration, and dissemination—in European, indigenous, and mixed or hybrid contexts—can be better understood by following their moveable parts, with a keen sensitivity toward non-normative epistemologies and more profound temporal frameworks.