The central action of betaaminopropylbenzene (benzedrine): clinical observations

MH Nathanson - Journal of the American Medical Association, 1937 - jamanetwork.com
Beta-aminopropylbenzene (benzedrine) is a compound of the epinephrine series
resembling ephedrine in chemical constitution, as shown in the structural formula. In 1910
Barger and Dale 1 made an exhaustive study of a large group of epinephrine-like
substances, with the conclusion that an action simulating that of true sympathetic nervous
stimulation is not peculiar to epinephrine but is possessed by a large number of amines
(substituted ammonias). These substances were termed sympathomimetic amines by Barger …