Rationale to study the early natural history of heart disease: the Bogalusa Heart Study
GS Berenson, WA Wattigney, W Bao… - The American journal of …, 1995 - Elsevier
ABSTRACT The Bogalusa Heart Study now establishes that precursors of adult
cardiovascular diseases begin in childhood. The clearest evidence comes from autopsy
studies that show coronary atherosclerotic lesions occur in early life and are strongly
associated with very—low-density lipoprotein cholesterol, systolic and diastolic blood
pressure, and obesity, and have an inverse relationship with high-density lipoprotein
cholesterol. Observations of cardiovascular risk factors span a period of life from birth to 31 …
cardiovascular diseases begin in childhood. The clearest evidence comes from autopsy
studies that show coronary atherosclerotic lesions occur in early life and are strongly
associated with very—low-density lipoprotein cholesterol, systolic and diastolic blood
pressure, and obesity, and have an inverse relationship with high-density lipoprotein
cholesterol. Observations of cardiovascular risk factors span a period of life from birth to 31 …