Although different health risks and behaviors displayed by contemporary U.S. immigrants create challenges for health care providers, knowledge on the health of and variations among African immigrant groups in the United States lags behind. This study compared health status, use of health care resources, and treatment strategies of 362 Ethiopian and Nigerian immigrants. The results indicated that mental health and English-speaking ability varied by country of birth. Furthermore, the study sample reported a low use of health care resources. These results suggest the existence of potential health issues among subsections of the African immigrant population that may threaten the maintenance of good health.