Serum indicators for the diagnosis of pneumocystis pneumonia

S Tasaka, N Hasegawa, S Kobayashi, W Yamada… - Chest, 2007 - Elsevier
Background The diagnosis of pneumocystis pneumonia (PCP) is difficult because it requires
microscopic examination to identify pneumocystis from induced sputum or BAL fluid. Study
objective To evaluate the usefulness of four serum markers—lactate dehydrogenase
(LDH),(1→ 3) β-D-glucan (β-D-glucan), KL-6, and C-reactive protein (CRP)—in the
diagnosis of PCP. Design Case-control retrospective study. Patients and measurements We
reviewed the medical records of 295 consecutive patients who underwent BAL for the …