The article illustrates some main trends in the field of generational audiences resulting from a study which explored social media use in intra and inter-generational communicative practices among four different generational cohorts. Furthermore, the research was focused on investigating how peer-to-peer and cross-generational web-based communicative practices could affect the three main sociological categories of reflexivity, space and memory. In addition, another research question was whether the social media use has any implications in peer-to-peer and cross-generational relationships. Across an ethnographic approach, twelve focus groups were conducted (N= 72) taking into account age and gender variables. The findings of the study suggest differences among the generational audiences in relation to the personal and collective aspects of reflexivity. Furthermore, the findings suggest that, also with generational differences, social media communicative practices play an important role in supporting inter-generational communication, affecting both the social space category and memory sharing. Finally, the research results suggest that, depending on the generational cohort investigated, social media practices play an important role in generational identity building or re-configuration.