Low blood lead levels associated with clinically diagnosed attention-deficit/hyperactivity disorder and mediated by weak cognitive control

JT Nigg, GM Knottnerus, MM Martel, M Nikolas… - Biological …, 2008 - Elsevier
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) and low-level lead exposure
are high-prevalence conditions among children, and studies of large populations have
suggested that these conditions are related. We examine this relationship in children from a
community sample exposed to average background levels of lead who have a diagnosis of
ADHD that is established by clinical criteria. METHODS: One hundred fifty children ages 8–
17 years participated (mean age= 14 years; 53 control subjects, 47 ADHD Predominantly …