In this Issue

Table of Contents

Clinical Research: twenty-five years of increasing concern for the linchpin of medical advances

Robert L. Perlman, Richard A. Rettig, Alan N. Schechter
p. 475
DOI: https://doi.org/10.1353/pbm.2004.0067
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Remembering the "Golden Years" of Patient-Oriented Clinical Research: a collective conversation

Judith P. Swazey, Renee C. Fox
pp. 487-504
DOI: https://doi.org/10.1353/pbm.2004.0073
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Denny-Brown, Boston City Hospital, and the History of American Neurology

Joel A. Vilensky, Sid Gilman, Pandy R. Sinish
pp. 505-518
DOI: https://doi.org/10.1353/pbm.2004.0074
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Children in Medical Research: balancing protection and access: has the pendulum swung too far?

Lainie Friedman Ross
pp. 519-536
DOI: https://doi.org/10.1353/pbm.2004.0069
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The Formation of the American Society of Clinical Oncology and the Development of a Medical Specialty, 1964-1973

Gretchen Marie Krueger
pp. 537-551
DOI: https://doi.org/10.1353/pbm.2004.0065
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Pathways of Innovation: a history of the first effective treatment for sickle cell anemia

Valerie L. Williams
pp. 552-563
DOI: https://doi.org/10.1353/pbm.2004.0076
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The UGDP Controversy: thirty-four years of contentious ambiguity laid to rest

Theodore B. Schwartz, Curtis L. Meinert
pp. 564-574
DOI: https://doi.org/10.1353/pbm.2004.0071
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The Role of Anemia in Congestive Heart Failure and Chronic Kidney Insufficiency: the cardio renal anemia syndrome

Donald S. Silverberg, Dov Wexler, Adrian Iaina
pp. 575-589
DOI: https://doi.org/10.1353/pbm.2004.0072
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From the Great Barrier Reef to a "Cure" for the Flu: tall tales, but true

William Graeme Laver
pp. 590-596
DOI: https://doi.org/10.1353/pbm.2004.0066
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The Fundamentals of Clinical Discovery

Jonathan Rees
pp. 597-607
DOI: https://doi.org/10.1353/pbm.2004.0068
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How Real is Fetal Alcohol Syndrome?

David T. Courtwright
pp. 608-616
DOI: https://doi.org/10.1353/pbm.2004.0062
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The Male Pill: a biography of a technology in the making (review)

G. M. H. Waites
pp. 617-623
DOI: https://doi.org/10.1353/pbm.2004.0075
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Darwin and the Barnacle: The Story of One Tiny Creature and History's Most Spectacular Scientific Breakthrough (review)

Peter C. Grosvenor
pp. 624-626
DOI: https://doi.org/10.1353/pbm.2004.0063
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Volume 47 Index

pp. 627-632
DOI: https://doi.org/10.1353/pbm.2004.0064
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Editors' Introduction: Why is Revitalizing Clinical Research So Important, Yet So Difficult?

Alan N. Schechter, Robert L. Perlman, Richard A. Rettig
pp. 476-486
DOI: https://doi.org/10.1353/pbm.2004.0070
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