Cases in Bioethics: Health Research Ethics in Southeast Asia
Key Words

HIV, STI, safety, stigma, stimulants, mental health, qualitative research, recruitment, MSM, social media, risks

Drug use during sexual encounters has become a growing concern globally among men who have sex with men (MSM)1, including in Southeast Asia.2 Stimulant drugs (crystal methamphetamine, ecstasy) and gamma-hydroxybutyrate are used by some MSM to facilitate and enhance sexual pleasure, a phenomenon known as "chemsex." During chemsex, sexual disinhibition and hypersexuality often lead to reduced condom use, sex with multiple partners, and other high-risk sexual behaviors, increasing the likelihood of HIV and Sexually Transmitted Infection (STI) transmission.3

MSM who participate in chemsex experience a range of physical, mental, and social harms associated with stimulant use and often have minimal access to HIV testing, prevention, and treatment services. As such, late HIV diagnosis is common in this high-risk population. Despite strict drug laws in Southeast Asia, stimulant use among MSM living in urban areas is on the rise, evident in gay dating apps and social media where stimulant-using MSM seek chemsex partners and share stimulant drugs.

After consulting MSM-serving nongovernment organisations for input on recruitment and data collection, a research team designed a qualitative study in a Southeast Asian country to explore the mental health needs of stimulant-using MSM, to increase HIV testing, and to link them to treatment. The researchers sought to recruit participants through targeted outreach via a social media app frequently used by MSM. A researcher set up a profile on the app to converse with men whose profiles suggested stimulant use. The researchers recruited individuals who were biological males aged 18 years or older who used stimulant drugs and had condomless anal intercourse in the past 3 months. Individual, in-depth interviews were conducted at mutually agreed locations, some at private residences.

Due to societal norms in this country and suspicion among stimulant-using MSM, recruitment was very difficult. To accommodate this challenge, the researcher became well-versed in the world of chemsex by learning the language and approaches used for sexual encounters and sharing drugs. Over time, this researcher gained the trust of the community, and recruitment went smoothly. The researcher obtained verbal consent after contacting individuals via phone screening and explaining the study procedure, risks, and benefits, then arranged face-to-face interviews. Upon meeting a participant at his home, the researcher discovered him unclothed and using crystal methamphetamine. Under the influence, the participant attempted to engage in sexual intercourse with the researcher. Shocked, the researcher abruptly left and conducted all remaining interviews at a research center.

Some participants remained in contact with this researcher after completion of the study, seeking social support in coping with their drug use problems. The researcher also interacted socially with some participants and encouraged the use of HIV prevention services.

Questions

  1. Are there ethical concerns about the inclusion criteria or recruitment procedures used in this study? If so, what alterations might be suggested?

  2. What challenges are associated with acquiring informed consent from individuals in this population? What strategies might help to address those challenges?

  3. How could safety be improved for both participants and the researcher? Does the institutional review board have a role in ensuring safety for researchers?

  4. Should researchers maintain a relationship with participants after a research project has been completed? Why or why not?

References

Bourne, A., D. Reid, F. Hickson, S. Torres-Rueda, and P. Weatherburn. “Illicit Drug Use in Sexual Settings (‘Chemsex’) and HIV/STI Transmission Risk Behaviour among Gay Men in South London: Findings from a Qualitative Study: Table 1.” Sexually Transmitted Infections 91, no. 8 (July 9, 2015): 564–68. https://doi.org/10.1136/sextrans-2015-052052.
Schmidt, Axel J., Adam Bourne, Peter Weatherburn, David Reid, Ulrich Marcus, and Ford Hickson. “Illicit Drug Use among Gay and Bisexual Men in 44 Cities: Findings from the European MSM Internet Survey (EMIS).” International Journal of Drug Policy 38 (December 2016): 4–12. https://doi.org/10.1016/j.drugpo.2016.09.007.
Vu, Nga Thi Thu, Lisa Maher, and Iryna Zablotska. “Amphetamine-Type Stimulants and HIV Infection among Men Who Have Sex with Men: Implications on HIV Research and Prevention from a Systematic Review and Meta-Analysis.” Journal of the International AIDS Society 18, no. 1 (January 2015): 19273. https://doi.org/10.7448/ias.18.1.19273.
Vu, Nga Thi Thu, Martin Holt, Huong Thi Thu Phan, Huong Thi Le, Lan Thi La, Gioi Minh Tran, Tung Thanh Doan, Trang Nhu Nguyen Nguyen, and John de Wit. “Amphetamine-Type Stimulant Use among Men Who Have Sex with Men (MSM) in Vietnam: Results from a Socio-Ecological, Community-Based Study.” Drug and Alcohol Dependence 158 (January 2016): 110–17. https://doi.org/10.1016/j.drugalcdep.2015.11.016.

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