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summary
Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries.

Table of Contents

  1. Cover
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  1. Title Page, Copyright Page
  2. pp. i-iv
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  1. Contents
  2. pp. v-vi
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  1. The Ernst Strüngmann Forum
  2. pp. vii-viii
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  1. List of Contributors
  2. pp. ix-xii
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  1. 1 - Introduction
  2. Karoly Nikolich and Steven E. Hyman
  3. pp. 1-6
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  1. Neurodevelopmental Disorders: A New Beginning
  2. pp. 7-8
  1. 2 - What Do We Know about Early Onset Neurodevelopmental Disorders?
  2. Thomas Bourgeron
  3. pp. 9-22
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  1. 3 - Psychotic Disorders andthe Neurodevelopmental Continuum
  2. Michael J. Owen
  3. pp. 23-40
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  1. 4 - Neurodevelopmental Disorders: What Is to Be Done?
  2. Stephan Heckers, Steven E. Hyman, Thomas Bourgeron, Bruce N. Cuthbert, Raquel E. Gur, Cynthia Joyce, Andreas Meyer-Lindenberg, Michael J. Owen, and Matthew W. State
  3. pp. 41-56
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  1. Neurodegenerative Diseases: Coming Unstuck
  2. pp. 57-58
  1. 5 - Neurodegenerative Diseases: Where Are We Not Looking for Answers?
  2. Walter J. Koroshetz and Lennart Mucke
  3. pp. 59-76
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  1. 6 - Preclinical and Clinical Understanding: Major Gaps in Our Understanding and Capabilities
  2. Edward H. Koo
  3. pp. 77-92
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  1. 7 - Neurodegenerative Diseases: What Is to Be Done?
  2. David M. Holtzman, Karoly Nikolich, Menelas N. Pangalos, Karl Broich, Nancy Y. Ip, Edward H. Koo, Walter J. Koroshetz, Eliezer Masliah, Lennart Mucke, Pierluigi Nicotera, Mareike Schnaars, and Maria Grazia Spillantini
  3. pp. 93-114
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  1. New Tools to Drive Future Therapies
  2. pp. 115-116
  1. 8 - How Might We Get from Genes to Circuits to Disease?
  2. Tobias Kaiser, Yuan Mei, and Guoping Feng
  3. pp. 117-126
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  1. 9 - How Do We Define and Modulate Circuits in Animals That Are Relevant to Pathophysiology in Humans?
  2. Joel S. Perlmutter
  3. pp. 127-138
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  1. 10 - Pathophysiological Toolkit: Genes to Circuits
  2. Gül Dölen, Robert C. Malenka, Joel S. Perlmutter, Nils Brose, Richard Frackowiak, Bruce N. Cuthbert, Ilka Diester, Isabelle Mansuy, Katja S. Kroker, Tobias M. Boeckers, Alvaro Pascual-Leone, Guoping Feng
  3. pp. 139-164
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  1. From Cellular and Animal Models to Patients
  2. pp. 165-166
  1. 11 - Using a Stem Cell-Based Approach to Model Neurodegenerative Disease: Where Do We Stand?
  2. Lee L. Rubin
  3. pp. 167-182
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  1. 12 - From Rodent Behavioral Models to Human Disorders
  2. Trevor W. Robbins
  3. pp. 183-208
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  1. 13 - Bridging the Gap between Patients and Models
  2. Ilka Diester, Franz Hefti, Isabelle Mansuy, Alvaro Pascual-Leone, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Marius Wernig, Gül Dölen, Steven E. Hyman, Lennart Mucke, Karoly Nikolich, and Bernd Sommer
  3. pp. 209-244
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  1. Epilogue
  2. pp. 245-246
  1. 14 - The Revolution Has Begun
  2. Steven E. Hyman and Karoly Nikolich
  3. pp. 247-254
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  1. Bibliography
  2. pp. 255-294
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  1. Subject Index
  2. pp. 295-304
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  1. Further Titles in the Strüngmann Forum Report Series
  2. pp. 305-306
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Additional Information

ISBN
9780262329859
Related ISBN
9780262029865
MARC Record
OCLC
919201534
Pages
352
Launched on MUSE
2015-08-28
Language
English
Open Access
No
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