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Biomedical Computing: Digitizing Life in the United States

Book
Joseph November
2012
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Winner of the Computer History Museum Prize of the Special Interest Group: Computers, Information, and SocietyImagine biology and medicine today without computers. What would laboratory work be like if electronic databases and statistical software did not exist? Would disciplines like genomics even be feasible if we lacked the means to manage and manipulate huge volumes of digital data? How would patients fare in a world absent CT scans, programmable pacemakers, and computerized medical records?Today, computers are a critical component of almost all research in biology and medicine. Yet, just fifty years ago, the study of life was by far the least digitized field of science, its living subject matter thought too complex and dynamic to be meaningfully analyzed by logic-driven computers. In this long-overdue study, historian Joseph November explores the early attempts, in the 1950s and 1960s, to computerize biomedical research in the United States.Computers and biomedical research are now so intimately connected that it is difficult to imagine when such critical work was offline. Biomedical Computing transports readers back to such a time and investigates how computers first appeared in the research lab and doctor's office. November examines the conditions that made possible the computerization of biology—including strong technological, institutional, and political support from the National Institutes of Health—and shows not only how digital technology transformed the life sciences but also how the intersection of the two led to important developments in computer architecture and software design. The history of this phenomenon has been only vaguely understood. November's thoroughly researched and lively study makes clear for readers the motives behind computerizing the study of life and how that technology profoundly affects biomedical research today.

Table of Contents

Cover

Title Page, Copyright Page

Contents

Acknowledgments

pp. ix-x

Abbreviations, Acronyms, and Initialisms

pp. xiii-xvi

Introduction

pp. 1-18

1 Putting Molecular Biology and Medical Diagnosis into Metal Brains: Operations Research and the Origins of Biomedical Computing

pp. 19-66

2 Building Tomorrow’s Biomedicine: The National Institutes of Health’s Early Mission to Computerize Biology and Medicine

pp. 67-123

3 The LINC Revolution: The Forgotten Biomedical Origins of Personal Computing

pp. 124-170

4 A New Way of Life: Computing in the Lab, in the Clinic, and at the Foundation

pp. 171-219

5 Martians, Experts, and Universitas: Biomedical Computing at Stanford University, 1960–1966

pp. 220-268

Conclusion

pp. 269-276

Notes

pp. 277-322

Essay on Sources

pp. 323-330

Index

pp. 331-344
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