This article historicizes the coronavirus pandemic experiences of two Latinx immigrant trans women by examining their oral histories within a broader social context. New Brunswick, New Jersey, is known as the "Health-Care City," although the significant Latinx population faces barriers to accessing quality health care. The article looks at the emergence of a trans immigrant community in this urban setting, nurtured, in part, by Oaxacan immigrants who have left an important cultural imprint on the city. Borrowing Joe Trotter's term, the article further suggests that trans immigrant women constitute a type of "industrial reserve" within a racialized workforce because anti-trans violence intensifies the disposability of their labor. The article explores how the pandemic exacerbated the ongoing social crises that shaped trans Latinx immigrant life in the city, particularly through an oral history with a COVID-19 survivor.