Michel Houellebecq's fiction is often perceived as essentially materialistic, in the sense that it follows the decline of humanity in the loss of transcendence, while every human interaction, including love and sex, is reduced to the logic of the capitalist market. Taking on a new materialistic approach, this article aims to challenge this presumption with readings that emphasize the vibrant, subversive nature of materiality in Houellebecq's fiction, particularly in the novels La carte et le territoire and Sérotonine. Drawing on recent new materialistic thought, I show that the shared destiny Houellebecq ascribes to both humans and objects under the logic of late capitalism makes, at times, this interdependence challenging to political economy. Vibrant matter, or the ex-nihilo rise of the "thing" from within the "object", becomes the ultimate rescue of both the human and the non-human in his novels. This perspective enables us to conceive of Houellebecq not merely as a pessimistic voice lamenting the decline of the human, but one that presents affirmative posthuman ethics, undermining the circulation of commodities, and of people as commodities, from the margins of the system itself.