This essay elaborates and engages a theopoetic reading mode to understand the function of lament in a selection of poems from the Crazy Women sections of Chilean Nobel laureate Gabriela Mistral's (1889–1957) Winepress (1954) and Wine-press II (1991). This method of reading will reveal how engaging the spatial metaphor of the relationship between human and God contributes to their tone of lament. Mistral's poetry articulates the sensation of insurmountable distance from the divine and shifts between despair and hope.