This article argues for the methodological resonance shared by Bruno Latour and William James in order to understand Latour’s affiliation with pragmatism. Unlike many readers of Latour, I suggest that his relation with pragmatism is primarily methodological rather than primarily ontological. To clarify this, I look to the resonances between James’s methodological pragmatism and Latour’s actor-network methodology. Latour’s pragmatism resonates with James’s as it incorporates a methodological focus on practices and objects, and as it furthers underdeveloped themes of motion in James’s pragmatism. This methodological alliance, I argue, consists in a modification of the metaphoric of method from one of Cartesian construction to one of movement and travel.