An individual’s genetic-relative family health history can lead to the identification of high-risk individuals and through this can result in highly effective disease prevention for those at risk. In this symposium, readers will see the very different lived experiences of adopted persons whose access to genetic-relative family health history is limited. All share a common experience of facing obstacles within the U.S. healthcare system related to lacking family health history. Genomic technologies now offer tremendous promise to fill gaps in access to this vital health information.