This response aims to critically evaluate the methodology and aims of the meta-analytic review written by Maggin and Johnson (2014). The present authors systematically provide responses for each of the original criticisms and highlight concerns regarding Maggin and Johnson’s methodology, while objectively describing the current state of evidence of the FRIENDS programs. The studies utilized for this response were conducted across cultural backgrounds and incorporated the most up-to-date methodology in prevention research. In review of the original article, this article raises concerns regarding the definition of prevention and risk, article identification and evaluation procedures, as well as overall methodology. Finally, it provides suggestions for future research in prevention and early intervention fields.