Many arts-focused colleges and universities in the United States offer their undergraduate students coursework in science. To better understand the delivery of science education at this type of institution, this article surveys the science programs of forty-one arts-oriented schools. The findings suggest that most science programs are located in general education departments alongside other liberal arts disciplines, and at most of the schools students are required to complete at least one science course. The findings also suggest that the context of science education at arts-focused colleges may encourage innovation in pedagogy and curriculum development. This article highlights courses and assignments from Emerson College and other schools in which scientific topics are aligned with arts fields or framed to emphasize the societal relevance of science and its place in our daily lives.