By accounting for the law’s productive capacity to structure asylum physicians’ encounters with suicide, this essay argues that the antebellum asylum was a technology for the preservation of life. The essay first shows how suicide’s history as a crime encouraged popular attributions of suicide to insanity. What began as a tactic to protect survivors, however, ended by bolstering the professional claims of asylum medicine. Initially it appeared there was much to gain from claiming suicide as their own, but dominion over prevention in fact rendered asylum physicians and their staffs vulnerable in unanticipated ways: for while agents of suicide were effectively evacuated of legal responsibility, a variety of laws made physicians more accountable than ever. Focusing on medical superintendent Amariah Brigham and his staff at the New York State Lunatic Asylum shows how the anxiety of assuming guardianship over the suicidal created networks of accountability that profoundly affected daily life.