This article uses insights from leadership studies to assess how individual leaders have influenced Lithuania’s presidential office and the country’s foreign policy. The case study examines the historical context under which this formal institution was created and evaluates the four presidents in terms of their effectiveness and the impact they had. The article concludes by identifying two Lithuanian leaders as being effective and influential during their presidency, albeit having different impacts on the foreign policy of the country due to their personality traits and domestic as well as foreign contextual factors.