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Evidence, Errors, and Ethics
- Perspectives in Biology and Medicine
- Johns Hopkins University Press
- Volume 57, Number 3, Summer 2014
- pp. 299-307
- 10.1353/pbm.2014.0024
- Article
- Additional Information
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Evidence-based decisions relating to the development and use of novel medical interventions are liable to false positive and false negative errors: adverse consequences that ensue from making or omitting to make a given decision. In this article we examine the propensity to false positive and false negative errors in light of competing value judgments in the areas of designing randomized controlled trials, pharmaceutical licensing, coverage of medical treatments, and clinical practice.