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This project places at its center the urgency for a more responsive organ transplant policy in the United States. It studies how relationships and affinity affiliations motivate intimate exchanges, including human biological markets. Specifically, the article considers whether affinity relationships might serve as a platform in the domain of organ transplantation and if so, whether the law should tolerate discriminatory behavior in the human biologics realm. In defining affinity relationships, the article speaks primarily to race, gender, and sexual orientation. Its theoretical underpinnings, however, could also apply to religion. The theoretical hunch of the article is that affinity relationships could play a role in motivating transplant procurement.