In lieu of an abstract, here is a brief excerpt of the content:

  • The Fusion of Tumor Cells with Host Cells;Reflections on an Ovarian Tumor
  • Russell L. Kerschmann, Bruce A. Woda, and Guido Majno
Russell L. Kerschmann
San Francisco General Hospital and the University of California at San Francisco, California 94110. Reprint requests.
Bruce A. Woda and Guido Majno
University of Massachusetts Medical Center, Worcester, Massachustts 01605


1. BLUMENTHAL, R. Membrane fusion. In Current Topics in Membranes and Transport, edited by F. BRONNER. Orlando: Academic Press, 1987.
2. MÜLLER, J. Über den feineren Bau und die Formen der krankhaften Geschwulste. Berlin: 1838.
3. WHITE, J. M., and BLOBEL, C. P. Cell-to-cell fusion. Curr. Opin. Cell. Biol. 1:934-939, 1989.
4. PAPADIMITRIOU, J. M. Macrophage fusion in vivo and in vitro: A review. In Membrane Fusion, edited by G. POSTE and G. L. NICOLSON. Amsterdam: Elsevier/North-Holland Biomedical Press, 1978.
5. RINGERTZ, N. R., and SAVAGE, R. E. Cell Hybrids. New York: Academic Press, 1976.
6. SCHLAFKE, S., and ENDERS, A. Cellular basis of interaction between trophoblast and uterus at implantation. Bio. Reprod. 12:41-65, 1975.
7. HARRIS, H. Cell fusion and the analysis of malignancy. Proc. R. Soc. Lond. B. 179:1-20, 1971.
8. DAGAN, D., and LEVITAN, I. B. Isolated identified Aplysia neurons in cell culture. J. Neurosci. 1:736-740, 1981.
9. ANGERT, E. R.; CLEMENTS, K. D.; and PACE, N. R. The largest bacterium. Nature 362:239-241, 1993.
10. WARWICK, R., and WILLIAMS, P. L. Gray's Anatomy, 35th ed. Philadelphia: W. B. Saunders, 1973.
11. GOLDSPINK, G. Development of muscle. In Differentiation and Growth of Cells in Vertebrate Tissues, edited by G. GOLDSPINK. New York: Wiley, 1974.
12. CHAMBERS, T. J. Studies of the phagocytic capacity of macrophage polykaryons. J. Pathol. 123:65-77, 1977.
13. BLACK, M. M., and EPSTEIN, W. L. Formation of multinucleated giant cells in organized epithelioid cell granulomas. J. Pathol. 74:263-270, 1974.
14. PAPADIMITRIOU, J. M., and CORNELISSE, C. J. A cytophotometric and autoradiographic study of DNA synthesis in macrophages and multinuclear foreign body giant cells. J. Reticuloend. Soc. 18:260-270, 1975.
15. PAPADIMITRIOU, J. M.; SFORSINA, D.; and PAPAELIAS, L. Kinetics of multinucleate giant cell formation and their modification by various agents in foreign body reactions. Am. J. Pathol. 73:349-362, 1973.
16. HARRIS, H. The genetic analysis of malignancy. J. Cell Sci. 4:431-444, 1986 (suppl).
17. KLIEN, G.; BREGULA, U.; and WIENER, F. The analysis of malignancy by cell fusion. I. Hybrids between tumour cells and L cell derivatives. J. Cell Sci. 8:659-672, 1971.
18. WEINBERG, A. W. Tumor suppressor genes. Science 254:1138-46, 1991.
19. LALA, P. K.; SANTER, V.; and RAHIL, K. S. Spontaneous fusion between Ehrlich ascites tumor cells and host cells in vivo: Kinetics of hybridization, and concurrent changes in the histocompatibility profile of the tumor after propagation in different host strains. Eur. J. Cancer 16:487-510, 1980.
20. LARIZZA, L.; SCHIRRMACHER, V.; GRAF, L.; et al. Suggestive evidence that the highly metastatic variant ESb of the T-cell lymphoma Eb is derived from spontaneous fusion with a host macrophage. Int. J. Cancer 34:699-707, 1984.
21. DE BAETSELIER, P. Neoplastic progression by somatic cell fusion. In Influence of Tumor Development on the Host, edited by L. A. LIOTTA. Netherlands: Kluwer Academic, 1989.
22. BER, R.; WIENER, F.; and FENYO, E. M. Proof of in vivo fusion of murine tumor cells with host cells by universal fusers: Brief communication. J. Nat. Cancer Inst. 60:931-933, 1978.
23. FENYÖ, E. M.; WIENER, F.; KLEIN, G.; and HARRIS, H. Selection of tumor-host cell...


Additional Information

Print ISSN
pp. 467-475
Launched on MUSE
Open Access
Back To Top

This website uses cookies to ensure you get the best experience on our website. Without cookies your experience may not be seamless.