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  • From Optical Activity in Quartz to Chiral Drugs:Molecular Handedness in Biology and Medicine
  • Ronald Bentley, Professor Emeritus
Ronald Bentley, Professor Emeritus
Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260

References

1. BROWNE, M. W. "Mirror image" chemistry yielding new products. The New York Times, 13 Aug. 1991, sect. B: 5, 8.
2. FDA's policy statement for the development of new stereoisomeric drugs. Chirality 4:338-340, 1992.
3. FEDER, B. J. Separating "mirror" molecules for better drugs. The New York Times, 12 Feb. 1992, sect. C: 7.
4. LEWIN, R. Chemistry in the image of biology. Science 238:611-612, 1987.
5. CHAIKEN, I.; CHIANCONE, E.; FONTANA, A.; and NERI, P., eds. Macromolecular Biorecognition: Principles and Methods. Clifton, N.J.: Humana Press, 1987.
6. ROBERTS, S. M., ed. Molecular Recognition: Chemical and Biochemical Problems. Vols. I, II. Cambridge: Royal Society of Chemistry, 1989, 1992.
7. HOLMSTEDT, B.; FRANK, H.; and TESTA, B., eds. Chirality and Biological Activity. New York: A. R. Liss, 1990.
8. BROWN, C., ed. Chirality in Drug Design and Synthesis. San Diego: Academic Press, 1991.
9. WILSON, K., and WALKER, J. Chirality and its importance in drug development. Biochem. Soc. Trans. 19:443-474, 1991.
10. SHELDON, R. A. Chirotechnology: Industrial Synthesis of Optically Active Compounds. New York: M. Dekker, 1993.
11. AMATO, I. Looking glass chemistry. Science 256:964-966, 1992.
12. CAHN, R. S.; INGOLD, C.; and PRELOG, V. Specification of molecular chirality. Angew. Chem. Internat. Edit. 5:385-415, 1966.
13. MISLOW, K. Introduction to Stereochemistry. New York: W. A. Benjamin, 1965.
14. BIELLMANN, J.-F. Chiralité du diptérocarpol en C-20. Tetrahedron Letters, 4803-4805, 1966.
15. MACDERMOTT, A. J. Distinguishing true chirality from its accidental imitators. Nature 323:16-17, 1986.
16. BARRON, L. D. True and false chirality and absolute asymmetric synthesis. J. Amer. Chem. Soc. 108:5539-5542, 1986.
17. KYBA, E. P.; SIEGEL, M. G.; SOUSA, L. R.; et al. Chiral, hinged, and functionalized multiheteromacrocycles. J. Amer. Chem. Soc. 95:2691-2692, 1973.
18. KYBA, E. P.; KOGA, K.; SOUSA, L. R.; et al. Chiral recognition in molecular complexing. J. Amer. Chem. Soc. 95:2692-2693, 1973.
19. JOB, R., and BRUICE, T. C. Chiral recognition of a prochiral (meso-carbon) centre by Λ(—)436-α-l,l-2,9-diamino-4,7-diazadecanecobaltate. J. Chem. Soc. Chem. Comm. 332-333, 1973.
20. HERSCHEL, J. F. W. On the rotation impressed by plates of rock crystal on the planes of polarization of the rays of light, as connected with certain peculiarities in its crystallization. Trans. Camb. Phil. Soc. 1:43-52, 1822.
21. PASTEUR, L. Researches on the Molecular Asymmetry of Natural Organic Products. Reissue edition published for the Alembic Club. Edinburgh: E. & S. Livingstone, 1948.
22. JAPP, F. R. Stereochemistry and vitalism. Nature 58:452-460, 1898.
23. HANEIN, D.; GEIGER, B.; and ADDADI, L. Differential adhesion of cells to enantiomorphous crystal surfaces. Science 263:1413-1416, 1994.
24. FRANKLAND, P. Pasteur Memorial Lecture. J. Chem. Soc. Trans. 71:683-743, 1897.
25. FISCHER, E. Ueber die Spaltung einiger racemischer Amidosäuren in die optisch-activen Componenten. Ber. dtsch. chem. Ges. 32:2451-2471, 1899.
26. FISCHER, E. Synthesen in der Zuckergruppe. Ber. dtsch. chem. Ges. 23:2114-2141, 1890.
27. FISCHER, E. Einfluss der Configuration auf die Wirkung der Enzyme. Ber. dtsch. chem. Ges. 27:2985-2993, 1894.
28. FISCHER, E., and BERGELL, P. Ueber die Derivate einiger Dipeptide und ihr Verhalten gegen Pankreasfermente. Ber. dtsch. chem. Ges. 33:2592-2608, 1903.
29. DAKIN, H. D. The hydrolysis of optically inactive esters...

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Additional Information

ISSN
1529-8795
Print ISSN
0031-5982
Pages
pp. 188-229
Launched on MUSE
2015-01-07
Open Access
No
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