-
Linkage Disequilibria and Haplotype Structure of Four SNPs of the Interleukin 1 Gene Cluster in Seven Asian Indian Populations
- Human Biology
- Wayne State University Press
- Volume 78, Number 1, February 2006
- pp. 109-119
- 10.1353/hub.2006.0026
- Article
- Additional Information
- Purchase/rental options available:
Variation at four single nucleotide polymorphism (SNP) sites of the interleukin 1 (IL1) gene cluster was investigated among 280 unrelated individuals, representing 7 caste groups from the state of Karnataka, India, and one European American community of Boston, Massachusetts. Allele and haplotype frequencies, strength of linkage disequilibrium, and signatures of recombination varied considerably among populations. Variable community sizes and traditions of consanguinity may account for the observed variation.