restricted access Part III: Understanding Lymphoma
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UV part iii Understanding Lymphoma The fInal part of thIs book Is focused less on understanding what it is like to experience lymphoma and lymphoma treatment and more on understanding the underlying disease. Chapter 9, “Basic Cell Biology and Cancer,” is an introduction to cell biology; I describe normal cells and explain how damage to an individual cell can disrupt the processes governing its behavior and lead to cancer. Toward the end of this chapter, I describe some of the specific cellular abnormalities that have been associated with lymphoma. In Chapter 10, “The Immune System,” I discuss lymphocytes and the immune system in which they function. Understanding the development and behavior of normal lymphocytes helps us to understand the behavior of the malignant lymphocytes that make up lymphoma. Armed with a basic knowledge of normal lymphocyte behavior, we can move on, in Chapter 11, “Lymphoma Classification and Staging,” to an in-depth discussion of abnormal lymphocytes. In this chapter, I describe the different forms of lymphoma: how they are classified, how they differ from each other, and why lymphoma classification has traditionally been considered so confusing. Finally, in Chapter 12, I discuss the causes of lymphoma —the things we are exposed to that can damage a lymphocyte so that it turns cancerous. The material in this part of the book is, necessarily, more technical than that in the first two parts. If you read the material carefully, however, and U 262 Understanding Lymphoma in the order in which it is presented, you will gain a true understanding of lymphoma. My goal is for readers to learn fundamental “lymphoma vocabulary ” and concepts of the field, so that they can make use of material about lymphoma found in the primary medical literature. ...