Holistic Views of Biological Structure
Publication Year: 1981
Published by: Hong Kong University Press, HKU
The University of Hong Kong has paid me a great compliment through its invitation to deliver this, the second, S. T. Huang-Chan Memorial lecture. It is an especial honour to give this lecture in the name of Mrs. Beatrice Huang (Dr. Chan Shu-Tzu) a colleague in the Department of Anatomy much mourned by the Department, the whole University, and her husband, microbiologist Emeritus Professor C. T. ...
The work described in this paper was carried out in the Universities of Birmingham, U.K., Chicago, and Southern California, U.S.A., during the years 1954-80. It has been supported by numerous NSF and NIH grants during those years. It is currently supported by NSF grant DEB 24366 and by funds from the University of Southern ...
1 STRUCTURE: From Visual Appreciation To Measurement
Though the study of biological structure has depended for centuries upon the visual appreciation of anatomies by the human eye and mind, it has rested for at least many decades upon the additional methods of measurement and analysis. In earlier times measurements were made with calipers, and simple univariate and bivariate statistics were the primary analytical methods available. In more recent times, measurements have come to be automated using electronic measuring devices, and ...
2 COMPLEXITIES OF STRUCTURE: The Shapes Of Groups
However, as we think about the possible structures that data may take up, it is clear that the matter may be far more complex. For instance, the moment that our data are in more than two or three dimensions, the moment, in other words, that more than three variables describe each point in our data, we have difficulty in recognising what the data show. And the moment that the data take up forms in which groups ...
3 COMPLEXITIES OF STRUCTURE: Interfaces Between Groups
Again, when we come to study the interfaces between groups, there are many different possibilities. Though figure 7 shows, left frame, an interface between two groups that is of simple, linear, form, it also demonstrates, middle frame, a more complex interdigitated arrangement that is easily seen in this two-dimensional example but which might be less easily recognised in the multi-dimensional ...
4 EXAMPLES FROM ANATOMY: Shoulders And Monkeys
It is clear, then, that if such data complexities truly exist within biological structures, we must have additional tools for coping with them. But if we are to save ourselves a great deal of work, we might first ask the question — do such complexities ever really exist in biology? The answer comes back loud and clear that they do; and I would like to present you with two examples from the rather early work on the ...
5 STRUCTURE: From Measurement To Field View
For this reason, then, a large part of our efforts over the last few years have been aimed at trying to move from simple ways of looking at measurements defining structures to more complex ways of analysing measurements representing structures. In other words we have been attempting to reclaim information inherent in measures of structures that were lost because the methods for analysing the ...
6 FIELD VIEW: Optical Data Analysis
The answer may lie to some degree within a series of methods that have been evolved in recent years to cope with the problems of characterising the complexity of a picture. These methods allow holistic appreciation of pictures such as photographs of sections and radiographs. These, though not themselves three-dimensional, can provide the three-dimensional information. ...
7 AGAIN, EXAMPLES FROM ANATOMY: Vertebrae And Apes
Such methods must be of interest to anatomists, of all scientists those most closely involved in the study of structure. And indeed, in our own work, they have proven most useful. We have been interested for many years in the relationship between internal architecture and stress bearing in bones. The chief view of this, an idea more than a century and a half old (see Culmann and Meyer as reported in Murray, 1936) ...
We have examined a gamut of questions about shape and structure. We have moved from visual examination of shape, through characterization and comparison using individual measurements one by one, through measurements put together by multivariate analysis, to quasi-continuous characterizations of shape in which field definitions are obtained by extrapolation between measured points. ...
Page Count: 48
Publication Year: 1981
OCLC Number: 650994658
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