The conduct of human subjects research in the wake of natural and man–made disasters is essential in order to further our understanding of the mental and behavioral health effects of such events on individuals and communities. The results of post–disaster research can better prepare public health systems to consider and address individual and community mental and behavioral health needs. In–depth interviews (n = 17) explored the ethical concerns and challenges encountered by investigators and IRBs in their review and conduct of post–disaster research. A variety of review mechanisms are described as well as the concerns of investigators and IRBs about the vulnerability of subjects and the challenges of conducting research in a community affected by disaster.


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